Depending on the free testosterone concentration in white men, this WMD translates into a racial difference ranging from 2.5 to 4.9%. After age adjustment, free testosterone levels were significantly higher in black than in white men (WMD = 4.07 pg/mL, 95% CI 1.26, 6.88). Fifteen eligible studies were identified three did not report adjusted means. A meta-analysis was performed using weighted mean differences (WMD) to compare hormones levels between black and white men. We searched PubMed for articles comparing circulating hormones in black and white men. The aim of this study was to assess racial variation in circulating testosterone, free testosterone, sex hormone-binding globulin (SHBG) and estradiol levels in men. However, it is currently unclear whether sex steroid hormone levels differ between black and white men. Sex steroid hormones are associated with chronic diseases and mortality with risk associations that differ between racial and ethnic groups.
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